A trailblazer in the realm of contemporary southwest art, De Mayo has been instrumental in pushing the envelope and abolishing the stereotypes of what the viewing public considers Southwestern. He utilizes dramatic color, the abstract, numbers and a bit of whimsy to enhance his images and message together with a bold, daring and controlled simplicity that fill his canvases. De Mayo is best known for his interpretation of the Native American spirit, however, in recent years, he has found a renewed passion in contemporary and realistic style.